Miscarriage and Uterine Lining EnzymeI suffered six miscarriages before I had my daughter. I frequently wonder if my change in diet and lifestyle might have changed my body chemistry to a point where I was able to conceive and carry to term. All of my doctors put me in the "unexplained" category...and some just called me "too old". But there may be more to the story.
If you've never heard of SGK1, you're not alone, I hadn't either. But, apparently, this enzyme in either high or low quantities may explain both infertility and miscarriage. Read more:
From the article:
Researchers from Imperial College London looked at tissue samples from the womb lining, donated by 106 women who were being treated at Imperial College Healthcare NHS Trust either for unexplained infertility or for recurrent pregnancy loss.
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The women with unexplained infertility had been trying to get pregnant for two years or more and the most common reasons for infertility had been ruled out. The researchers discovered that the womb lining in these women had high levels of the enzyme SGK1. Conversely, the women suffering from recurrent pregnancy loss had low levels of SGK1.